“Click-Once” loops to install .NET Framework

 When starting a „Click-Once“ published application from Internet URL a dialog keeps trying to install .NET Framework every time, and even if you run this install it keeps trying to install .NET Framework on subsequent „Click-Once“ activations…

And you are sure – .NET Framework is installed on your PC. What’s this?

This is caused when you opened a .application file in e.g. Notepad and set Notepad to be the default handler for .application files. (It needs to be the ClickOnce client runtime component). Resetting this back to the default handler corrected the problem.

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